KMID : 0614620230810040163
|
|
Korean Journal of Gastroenterology 2023 Volume.81 No. 4 p.163 ~ p.167
|
|
Two Case Reports of Newly Diagnosed Crohn¡¯s Disease after COVID-19 in Pediatric Patients
|
|
Kim Kuk-Won
Kim Su-Yeon Kim Young-Eun Kwon Kye-Won Han Eun-Mee Kim Ah-Lee
|
|
Abstract
|
|
|
Since the coronavirus disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome-coronavirus-2 virus (SARS-CoV-2), various complications have been reported. Although most COVID-19 cases exhibited flu-like symptoms, COVID-19 may dysregulate the immune response and promote overwhelming levels of inflammation in some patients. Inflammatory bowel disease (IBD) is caused by dysregulated or inappropriate immune responses to environmental factors in a genetically susceptible host, and a SARS-CoV-2 infection may act as a possible cause of IBD. This paper describes two pediatric patients who developed Crohn¡¯s disease following a SARS-CoV-2 infection. They were previously healthy before the SARS-CoV-2 infection. On the other hand, they started to develop fever and gastrointestinal symptoms several weeks after recovery from the infection. They were diagnosed with Crohn¡¯s disease by imaging and endoscopic studies, and their symptoms improved after treatment with steroids and azathioprine. This paper suggests that a SARS-CoV-2 infection may trigger IBD in predisposed patients.
|
|
KEYWORD
|
|
COVID-19, SARS-CoV-2, Inflammatory bowel disease, Crohn disease, Pediatric multisystem inflammatory disease
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|